This is a picture of railroads between New York and San Francisco, soon after the construction of the transcontinental railroad. It shows several destinations across the country in between as well. The web page says it may actually be a board game! A better-quality image can be found at this link: http://imgzoom.cdlib.org/Fullscreen.ics?ark=ark:/13030/tf409nb5ps/z1&&brand=oac4
I found this on Calisphere, which is a digital archive that compiles materials from California’s college and public libraries.